In vitro inhibitory activity of garlic and ginger extracts on some respiratory tract isolates of gram-negative organisms

Abstract

Fresh rhizomes of Ginger and cloves Garlic were collected, air-dried at room temperature and extracted separately using ethanol as solvent of extraction. The extracts were tested for antimicrobial activity against respiratory tract isolates of Pseudomonas aeruginosa, Morganella morganii, Providencia specie, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis and Proteus vulgaris. The antimicrobial activity of ginger and garlic extracts on test isolates was determined using disc diffusion method. The results of sensitivity tests indicated that ethanolic extracts of both ginger and garlic have in vitro inhibitory activity against all isolates of Gram-negative organisms tested and sensitivity of the isolates increases with increase in concentration. Ethanolic extract of Garlic showed greater in vitro inhibitory activity than that of Ginger against all isolates tested.