The effects of aqueous extract of Mangifera indica on protein, glucose concentration and enzyme activities of some rat tissues

Abstract

The effects of aqueous extract of the bark of Mangifera indica, a widely used antimalarial medicinal plant on enzyme activities of some rat tissues were studied.  The enzymes assayed were alkaline phosphatase (ALP), alanine transaminase (ALT), and aspartate transaminase (AST), protein and glucose were also analyzed.

      The results obtained showed that there was decrease in the activities of these enzyme in the liver and the heart when the aqueous extract was administered to the rats, this indicates tissue damage which was complimented with an increase in the activities of these enzymes in the blood due to leakage to the blood.  This shows that prolonged usage of the aqueous extract of the bark of Mangifera indica may lead to cell destruction.