EFFECT OF ORAL AMODIAQUINE ADMINISTRATION ON SOME HOMEOSTATIC VARIABLES IN HEALTHY NIGERIANS

Abstract

The effects of oral amodiaquine (aq) on blood glucose, blood pressure and urinary electrolytes were investigated in six healthy male young adults. Amodiaquine caused a fall in blood pressure without hypotensive features and a fall in blood glucose without hypoglycaemic symptoms. There were no disturbances in electrolyte balance. Amodiaquine may therefore be used in dehydrated patients without the fear of worsening electrolyte balance in such patients.