Isolation and antibiotic sensitivity of Escherichia coli from pregnant and non-pregnant women attending the University of Maiduguri Teaching Hospital (UMTH), Maiduguri, Nigeria

Abstract

This study was carried out to isolate and determine the antimicrobial susceptibility patterns of Escherichia coli from pregnant and non-pregnant women with urinary tract infection attending University of Maiduguri Teaching Hospital (UMTH) Maiduguri, Nigeria from   X- 2008.Clean voided mid-stream urine samples were collected in sterile universal bottles while high vaginal swab samples were obtained from patients with the use of sterile swab stick. A total of 260 samples were collected comprising 65urine samples each from pregnant and non-pregnant women and 65 high vaginal swabs each from pregnant and non-pregnant women.

      The results showed that out of the sixty-five (65) urine samples collected from pregnant women attending the health institutions, 48 (73.9%) were positive for various species of bacteria which includes Escherichia coli 26 (40.0%), Staphylococcus aureus 10 (15.4%), Proteus species (15.4%) and Klebsiella species 2 (3.1%). Out of the 65 high vaginal swab samples collected from the pregnant women, 16 (24.6%) were positive for various species of bacteria among which are Escherichia coli 7 (10.8%), Staphylococcus aureus 6 (9.2%), Proteus species 3 (4.6%).

     Out of the sixty-five (65) urine samples collected from non-pregnant women attending the health institutions, 33(50.8%) were positive for various species of bacteria which includes Escherichia coli 15 (23.1%), Staphylococcus aureus 10 (15.4%) and Proteus species 8 (12.3%). Out of the 65 high vaginal samples collected from non-pregnant women attending the health institutions 17 (26.1%) were positive for the following species of bacteria, Escherichia coli 6 (9.2%), Staphylococcus aureus 5 (7.7%) and Proteus species 6 (9.2%).

     The result of antibiotic sensitivity test on E.coli isolates showed that they are highly sensitive to the quinolone group of antibiotics such as Ciprofloxacin, Ceporex and Perflacin. The organism is intermediate sensitive to Streptomycin, Tarivid and Gentamycin but resistant to Augmentin, Nalidixic acid, Septrin and Ampicillin.