Determination of Dissociation Constants of Amino Acids Using ‘ORIGIN 50’ Program

Abstract

Potentiometric Studies on the dissociation constants of amino acids were carried out. The dissociation constants of amino acids were determined using ‘ORIGIN 50’ Program, as an attempt to find an alternative way for determination of the dissociation constants of amino acids, pKa, instead of the conventional calculation methods. The dissociation constants of amino acids determined are; alanine (10.29), arginine (12.02), asparagine (9.39), glycine (9.87), histidine (7.01), lysine (9.28), methionine (9.68), phenyalanine (9.61), proline (10.53), threonine (10.31), tryptophan (9.77), and valine (10.28)